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KMID : 1001020100080030138
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Korean Journal of Urological Oncology
2010 Volume.8 No. 3 p.138 ~ p.143
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Predictive Factors for Pathologically Benign Lesions among Small (≤4cm) Renal Masses Suspicious for Malignancy
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Hong Sung-Kyu
Lee Won-Ki
Na Woong
Nam Jung-Soo
Oh Jong-Jin
Jeong Chang-Wook
Byun Seok-Soo
Lee Sang-Eun
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Abstract
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Purpose: We tried to identify potential preoperative predictors of benign histology among small (≤4cm) renal masses presumed to be malignant by analyzing a contemporary cohort of patients who received surgical management for such renal lesions.
Materials and Methods : We reviewed records of 202 patients who received radical or partial nephrectomy for small (≤4cm) enhancing renal mass deemed suspicious for malignancy between 2004 and 2009. Both uniand multivariate logistic regression models were applied to examine the potential association of various preoperative variables with benign histology of small renal mass. A receiver operator characteristics (ROC) curve was applied to assess accuracies of potential predictors.
Results: Of the 207 small renal masses resected from 202 patients, 20 (9.7%) were found to be pathologically benign lesion. Among various preoperative factors, only female gender (p=0.041) and smaller tumor size measured on preoperative computed tomography scan (p=0.049) were observed to be independent predictors of benign histology in multivariate analysis. Areas under ROC curves for gender, tumor size, and predictive model combining the two variables were 0.611, 0.615, and 0.681, respectively, demonstrating no significant differences among the three curves (all p＞0.05).
Conclusions : Although gender and tumor size were identified to be independent predictors of benign histology for small renal masses deemed suspicious for malignancy, the levels of accuracies for the two predictors were observed to be less than satisfactory. Further efforts should be made to improve the diagnostic approaches for small renal mass suspicious for malignancy.
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KEYWORD
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Benign, Kidney, Pathology, Small renal mass
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